The Multi Drug 5 Drug Urine Multi-Line Screen Test
The Multi Drug 5 Drug Urine Multi-Line Screen Test is a one-step immunochromatographic assay for the rapid qualitative detection of Cocaine (COC), Amphetamine (AMP), Methamphetamine (MET), Opiates (OPI) and Tetrahydrocannabinol (THC) in human urine. CLIA WAIVED. This test kit is more convenient to use with sharp lines that can easily seen for less risk of mistake. Sensitivity cut-off test for the five drugs are as follows:
300 ng/ml - COC
1000 ng/ml - AMP
1000 ng/ml - MET
300 ng/ml - OPI
50 ng/ml - THC
The above mentioned drugs are the most commonly abused drugs and preventing children from being involved in such a complex problem like drug abuse is one of the bigger challenges any parent has to face. Most parents that are aware of the importance of establishing open communication regarding the matter choose to establish a Family Drug and Alcohol Policy with their children.
This policy includes drug education, statement of expectations, a listing of specific restrictions and potential for drug testing. The reality of drug testing should be understood by children. For some, it has provided an acceptable excuse to their peers to say no.
EXPLANATION OF THE TEST
COC derived from the leaves of the coca plant, is a potent central nervous system stimulant and a local anesthetic. Cocaine induces euphoria, confidence and a sense of increased energy in the user; these psychological effects are accompanied by increased heart rate, dilation of the pupils, fever, tremors and sweating. Cocaine is used by smoking, intravenous, intranasal or oral administration, and excreted in the urine primarily as benzoylecgonine in a short time. Benzoylecgonine has a longer biological half-life (5-8 hours) than cocaine (0.5-1.5 hours) and can generally be detected for 24-80 hours after cocaine use or exposure.
AMP is class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body's natural catecholamine, epinephrine and norepinephrine. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. More acute responses produce anxiety, paranoia, hallucinations, and psychotic behavior. The effects of amphetamines generally last 2-4 hours following use, and the drug has a half-life of 4-24 hours in the body. About 30% of amphetamines are excreted in the urine in unchanged form, with the remainder as hydroxylated and deaminated derivatives.
MET is a potent sympathomimetic agent with therapeutic applications. The drug can be taken orally, injected, or inhaled. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to MET include increased blood pressure and cardiac arrhythmias. More acute responses include anxiety, paranoia, hallucinations, psychotic behavior, and eventually, depression and exhaustion. The effects of MET generally last 2-4 hours, and the drug has a half-life of 9-24 hours in the body. MET is excreted in the urine primarily as amphetamine and oxidized and deaminated derivatives. However, 10-20% of MET is excreted unchanged. Thus, the presence of the parent compound in the urine indicates MET use. MET is generally detectable in the urine for 3-5 days, depending on urine pH level.
Opioid analgesics comprise a large group of substances, which control pain by depressing the central nervous system. Morphine is the prototype compound of this group. Morphine is excreted in the urine primarily as morphine-3-glucuronide while smaller amounts are excreted as unchanged free morphine and other metabolites. It is also the major metabolic product of codeine and heroin. Morphine is delectable in the urine for several days after an opiate dose.
THC (9-tetrahydrocannabinol) is the primary active ingredient in cannabinoids (marijuana). When ingested or smoked, it produces euphoric effects. Users have impairment of short-term memory and THC use slows learning. Also, it may cause transient episodes of confusion, anxiety, or even frank toxic delirium. Long term, relatively heavy use may be associated with behavioral disorders. The peak effect of smoking THC occurs in 20-30 minutes and the duration is 90-120 minutes after one cigarette. Elevated levels of urinary metabolites are found within hours of exposure and remain detectable for 3-10 days after smoking. The main metabolite excreted in the urine is 11-nor- 9-tetrahydrocannabinol-9-carboxylic acid.
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